<p>Principles of Clinical Pharmacology is a free online lecture series run by the NIH Office of Clinical Research Education and Collaboration Outreach (OCRECO). The course covers the fundamentals of clinical pharmacology as a translational discipline for rational drug development and therapeutics.</p><ul><li>Topics: pharmacokinetics, drug metabolism and transport, drug therapy in special populations, assessment of drug effects, drug discovery and development, pharmacogenomics, and pharmacotherapy.</li><li>Seven modules with 48 pre-recorded core lectures; each lecture is paired with a case study or post-lecture activity.</li><li>Online final exam of 25-50 multiple-choice questions; participants may use course materials during the exam.</li><li>Certificate of Completion awarded to registered participants scoring 70% or higher on the final exam; no CME credit offered.</li><li>2025-2026 cycle: registration runs 2 Sep 2025 to 26 Jun 2026; course access closes 31 Jul 2026; final-exam deadline 16 Jul 2026.</li></ul><p>Register via the OCRECO course page to gain access and take the final exam; non-registered learners can still view individual lectures on the NIH PCP YouTube playlist or NIH VideoCast.</p>